abstract：:The Val617Phe point mutation of Janus kinase 2 gene is believed to participate in the pathogenesis of myeloproliferative syndrome characterised by the clonal alteration of hematopoietic stem cells. According to current results, the frequency of Val617Phe activating mutation is around 80% in polycythaemia vera, 35% in ...

journal_title：Orvosi hetilap

authors： Andrikovics H,Szilvási A,Meggyesi N,Király V,Halm G,Lueff S,Nahajevszky S,Mikala G,Sipos A,Lovas N,Csukly Z,Mátrai Z,Tamáska J,Tordai A,Masszi T

更新日期：2007-02-04 00:00:00

abstract：INTRODUCTION:In the last few years the rapid development of flexible endoscopies has opened new possibilities in minimal invasive procedures. With the help of these techniques the exposure, the risk of complications and the healing period of the patient might be reduced. One of these procedures is the transgastric inte...

journal_title：Orvosi hetilap

authors： Lukovich P,Kádár B,Jónás A,Sadatakhavi M,Váradi G,Tari K,Kupcsulik P

更新日期：2007-01-28 00:00:00

abstract：UNLABELLED:Treatment and prognosis of bacteremias caused by Staphylococcus aureus is different, whether only bacteremia is present or it is complicated with endocarditis. Transoesophageal echocardiography may have a role in evaluation of bacteremias caused by Staphylococcus aureus to confirm or exclude infective endoca...

journal_title：Orvosi hetilap

authors： Bálint OH,Temesvári A,Prinz G

更新日期：2007-01-14 00:00:00

abstract：INTRODUCTION:Human metapneumovirus was identified in 2001 as a respiratory-tract pathogen that has been classified as a new genera in family Paramyxoviridae. AIMS:Molecular detection of human metapneumovirus in Hungary. MATERIALS AND METHODS:Human metapneumovirus was identified in nasopharyngeal aspirate amplificatio...

journal_title：Orvosi hetilap

authors： Reuter G,Szabó H,Székely G,Gyurkovits K,György S

更新日期：2006-12-03 00:00:00

abstract：:Low HDL cholesterol level is an independent risk factor in the cardivascular diseases and the therapeutic aim is to increase this. In high risk patients (cardiovascular disease-, diabetic- or metabolic syndrome patients), the target value of HDL cholesterol is more than 1,0 mmol/l in males and 1,3 mmol/l in females. T...

journal_title：Orvosi hetilap

authors： Kalina A

更新日期：2006-11-26 00:00:00

abstract：INTRODUCTION AND METHODS:The authors analysed the data of 307 live-birth newborns and premature infants who were born from 104 triplet pregnancies between 1 January 1990 and 31 December 2005 at the Semmelweis University First Department of Obstetrics and Gynecology. AIMS AND RESULTS:In 86% of the triplet pregnancies c...

journal_title：Orvosi hetilap

authors： Sassi L,Görbe E,Hruby E,Perlaki M,Jeager J,Papp Z

更新日期：2006-11-12 00:00:00

abstract：:Diagnosis and management of endocrine crises in adulthood. The homeostasis of the body is regulated by concerted action of the endocrine, nervous and immune systems. An imbalance in this equilibrium, as a consequence of disease or endocrine failure, may lead to crisis, characterized by sudden onset and severe symptoms...

journal_title：Orvosi hetilap

authors： Vadász J

更新日期：2006-11-05 00:00:00

abstract：BACKGROUND:Neoadjuvant therapy has improved outcomes for patients with locally advanced rectal cancer. AIM AUTHORS: We studied the degree of histopathological regression after radiotherapy regimens commonly used in their clinical practice, and its effect on the pathology of by clinically founded T3-T4 rectal cancer. P...

journal_title：Orvosi hetilap

authors： Mátrai Z,Lövey J,Hitre E,Orosz Z,Gödény M,Péley G,Sulyok Z,Rényi Vámos F,Farkas E,Köves I

更新日期：2006-10-22 00:00:00

abstract：INTRODUCTION:The indications of digoxin therapy has been significantly narrowed and also the effective target therapeutic blood level has been decreased (0.9 micromol/L) compared to the previously desired one. OBJECTIVE:In this retrospective trial the data of 60 consecutive patients over 65 years (25 male, 35 female, ...

journal_title：Orvosi hetilap

authors： Erdei F,Vendrey R,Dani G,Kovács E,Márk L,Katona A

更新日期：2006-10-15 00:00:00

abstract：:Cerebral ischemia, caused by disturbance of the blood supply to the brain, is a major cause of death in our days. Diabetes mellitus exacerbates neuronal death induced by an ischemic insult. It is important to characterize the underlying mechanism of the cell damage in order to design therapeutic agents. The purpose of...

journal_title：Orvosi hetilap

authors： Murányi M,Lacza Z

更新日期：2006-10-01 00:00:00

abstract：:Congenital absence of the ductus venosus is a rare anomaly. The authors have found 57 cases in the literature. Their case was associated with a complex congenital heart disease, what occurs only in 10% of absent ductus venosus cases. In cases, where the umbilical vein connects directly to the right atrium, the volume ...

journal_title：Orvosi hetilap

authors： Hajdú J,Csapó Z,Rigó J Jr,Marton T,Pete B,Papp Z

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The risk of colorectal carcinoma development is elevated in chronic, longstanding ulcerative colitis. The changes of such regenerative and immortalizing pathways caused by the inflammatory process that are proved to be carcinogenic in other human tissues have not been fully and uniformly described. Aim of th...

journal_title：Orvosi hetilap

authors： Sipos F,Molnár B,Zágoni T,Miheller P,Tulassay Z

更新日期：2006-09-24 00:00:00

abstract：:In the androgen insensitivity syndrome (AIS) the androgen effect is decreased in the fetus and the youth despite the adequate testosterone production. Usually the mutation of the androgen receptor is responsible for the disease. In the presented case the external genitalia were similar to female genitalia but masses w...

journal_title：Orvosi hetilap

authors： Luczay A,Sólyom J,Hiort O,Szabó E,Dobos M,Jenovári Z,Fekete G

更新日期：2006-09-17 00:00:00

abstract：:Chronic renal failure remain the most significant cause of morbidity and mortality in patients with anorectal malformation. The urological anomalies associated with anorectal malformations are not only anatomical, but also functional, the latter being related to congenital neurovesical dysfunction. The neurovesical dy...

journal_title：Orvosi hetilap

authors： Bán G,Németh P,Túri S

更新日期：2006-08-27 00:00:00

abstract：:The Authors present a female patient who suffered from alopecia areata caused by extreme solar abuse. Biological effects of ionizing radiation, the damages by free radicals and protection against oxidative damage are summarized. The main forms and risk factors of UV-radiation, skin damages by UV-light as well as the p...

journal_title：Orvosi hetilap

authors： Cserhalmi M,Hagymási K,Szentmihályi K,Fehér J

更新日期：2006-08-20 00:00:00

abstract：:The etiology of granulomatous hepatitis is extremely extensive for which the granulomatous reaction induced hepatic inflammation is characteristic. In the majority of cases it is part of a systemic disease but sometimes there is primer hepatic lesion in the background. The 21 year-old Caucasian female patient was take...

journal_title：Orvosi hetilap

authors： Németh E,Bugovics E,Lengyel G,Pécsi G,Schaff Z,Fehér J

更新日期：2006-08-06 00:00:00

abstract：INTRODUCTION:Adult-onset acid maltase deficiency myopathy is a rare lysosomal storage disease with an autosomal recessive pattern of inheritance. The disease can be manifested with respiratory insufficiency and fatigue. METHODS:A case of a 45-year-old male patient is presented, and difficulty in diagnosis is discussed...

journal_title：Orvosi hetilap

authors： Merkli H,Pál E,Nagy F,Horváth R,Várdi VK,Komoly S,Illés Z

更新日期：2006-07-30 00:00:00

abstract：:(-)-Deprenyl, the irreversible inhibitor of monoamine oxidase B, has been used for decades in the therapy of Parkinson's disease. It improves parkinsonian symptoms due to its dopamine potentiating and antioxidant properties and presumedly delays disease progression. Its complex pharmacological action cannot be explain...

journal_title：Orvosi hetilap

authors： Pálfi M,Szökó E,Kálmán M

更新日期：2006-07-09 00:00:00

abstract：:No effective medical therapies have been developed sofar to enhance blood flow in the legs of patients with peripheral arterial disease (PAD). For patients with limb threatening ischaemia the only option for relief of rest pain or gangraena is amputation. There is evidence in experimental and clinical studies that adu...

journal_title：Orvosi hetilap

authors： Boda Z,Veréb Z,Rajnavölgyi E

更新日期：2006-06-25 00:00:00

abstract：:The redox homeostasis of patients with inflammatory bowel disease is not balanced because of malnutrition and malabsorption. The seriousness of this illness often hinders the intake and use of bioactive agents. We have just a small amount of knowledge about how patients can get access to these important materials. The...

journal_title：Orvosi hetilap

authors： Dörnyei O,Kovács A,Székely E,Dinya E,Blászovics A

更新日期：2006-06-11 00:00:00

abstract：:Graves' orbitopathy or thyroid associated orbitopathy is the most frequent extrathyroidal manifestation of Graves' disease with autoimmune mechanism which is still incompletely understood. The epidemiologic data provided evidence that severe, infiltrative orbitopathy is present in 3-5% of patients, and the quality of ...

journal_title：Orvosi hetilap

authors： Balázs C

更新日期：2006-06-04 00:00:00

abstract：:The case of a bilateral total knee arthroplasty in a hemophiliac patient is presented below. Postoperative blood loss, required factor substitution, complications after surgery were observed. Functional results were evaluated using the Hospital for Special Surgery Score. The pathophysiology of hemophilic arthropathy i...

journal_title：Orvosi hetilap

authors： Skaliczki G,Bartha L,Sólyom L,Nemes L

更新日期：2006-05-21 00:00:00

abstract：UNLABELLED:The incidence of proximal tumours in Western countries has steadily increased while that of distal tumours has shown a corresponding decrease. Our aim was to investigate the prevalence, location and histology of colorectal cancers in the last twelve years in Hungarian patients. PATIENTS AND METHODS:Clinical...

journal_title：Orvosi hetilap

authors： Fuszek P,Horváth HC,Speer G,Papp J,Haller P,Halász J,Járay B,Székely E,Schaff Z,Papp A,Bursics A,Harsányi L,Lukovich P,Kupcsulik P,Hitre E,Lakatos PL

更新日期：2006-04-23 00:00:00

abstract：AIM:The authors sought to investigate the occurrence of complications and adverse events among patients participating in phase II. Residential cardiac rehabilitation program after coronary event (myocardial infarction, transluminal coronary angioplasty or coronary artery bypass graft operation) and determine the factor...

journal_title：Orvosi hetilap

authors： Simon A,Berényi I,Tiringer I,Veress G

更新日期：2006-04-16 00:00:00

abstract：:The combination of pegilált interferon plus ribavirin is significantly more effective than conventional interferon plus ribavirin, and is thus the current therapy of choice for patients with chronic hepatitis C. Forty-eight weeks of treatment with combination of pegilált interferon plus ribavirin has produced overall ...

journal_title：Orvosi hetilap

authors： Werling K,Tulassay Z

更新日期：2006-04-09 00:00:00

abstract：:Overweight and obesity are worldwide problems, its health and psychosocial burden on the individual and on society are tremendous. Diagnosing obesity is rather easy, and is based on simple anthropometric measurements, such as body weight, height and waist circumference. The different classes of obesity are determined ...

journal_title：Orvosi hetilap

authors： Juhász A,Katona E,Csongrádi E,Paragh G

更新日期：2006-04-02 00:00:00

abstract：:The authors present the case of a fifteen-year-old anorectic girl. Her lowest body weight was after admission 16.5 kg, with a height of 139 cm-s (body mass index: 8.54 kg/m2). After five-year long unsuccessful individual therapy family therapy was administered, which caused remission, ascertained by a five-year follow...

journal_title：Orvosi hetilap

authors： Túry F,Wildmann M

更新日期：2006-03-19 00:00:00

abstract：:It is an important modern trend to try to modify the surface properties of titanium implants with titanium oxide produced in various ways. One possibility of surface modification is the formation of an oxide layer by heat and electric treatment. The authors examined three osteosynthesis plates treated with anodic oxid...

journal_title：Orvosi hetilap

authors： Velich N,Kovács L,Németh Z,Szabó G

更新日期：2006-03-05 00:00:00

abstract：:Chronic C hepatitis is a global health problem. Its treatment is still unresolved. Pegylated interferon means substantive breakthrough in therapy. The longer effect, the lasting, steady therapeutic blood level are the pharmacokinetic advances. There is no significant difference in the side effects of pegylated interfe...

journal_title：Orvosi hetilap

authors： Halász T,Farkas A,Tolvaj G,Horváth G

更新日期：2006-02-19 00:00:00

abstract：INTRODUCTION:Recent evidence raised the possibility that low-dose antipsychotic treatment during the prodromal phase may prevent the development of full-blown psychosis. AIMS:To investigate the effectiveness of low-dose antipsychotic medication in the prevention of psychosis. METHODS:Fifty-two persons who fulfilled t...

journal_title：Orvosi hetilap

authors： Kéri S,Kelemen O,Janka Z

更新日期：2006-02-05 00:00:00

abstract：:Increased cardiovascular risk in diabetes mellitus has been well-documented. In contrast, it is not widely known, that the relation between degree of hyperglycemia and mortality of diabetics or nondiabetics with acute coronary syndromes (ACS) shows a positive correlation. Insulin treatment significantly improves survi...

journal_title：Orvosi hetilap

authors： Simon K,Szépvölgyi A,Dobó E,Szabó A

更新日期：2006-01-22 00:00:00

abstract：:Rickettsia helvetica belonging to spotted fever group rickettsiae was recently detected by polymerase chain reaction followed by sequencing in European sheep ticks (Ixodes ricinus) from Hungary. Current knowledge on these rickettsiae and the clinical and diagnostic aspects of R. helvetica infection is summarized. In a...

journal_title：Orvosi hetilap

authors： Sréter T,Sréterné Lancz Z,Széll Z,Egyed L

更新日期：2005-12-11 00:00:00

abstract：:Myocardial infarction is the leading cause of congestive heart failure in the industrialized world. Current treatments fail to address the underlying scarring and cell loss, which are the causes of ischaemic heart failure. Recent interest has focused on stem cells, which are undifferentiated and pluripotent cells that...

journal_title：Orvosi hetilap

authors： Vértesaljai M,Piróth Z,Fontos G,Andréka G,Font G,Szánthó G,Réti M,Masszi T,Andréka P

更新日期：2005-11-20 00:00:00

abstract：INTRODUCTION:Hepatitis E virus (HEV) one of the most important infectious agent in acute hepatitis in tropical and subtropical areas. Recently, it has been demonstrated that HEV infection also occur in developed countries without travel history. In these regions, transmission thought to be zoonotic. In this work hepati...

journal_title：Orvosi hetilap

authors： Fodor D,Kátai A,Reuter G,Maszárovics Z,Menyhárth E

更新日期：2005-11-06 00:00:00

abstract：INTRODUCTION:In 1978 the authors studied a male gypsy child with a multiple malformation syndrome. In this gypsy colony further five cases were found with similar features. The characteristic syndrome was published in 1980. Subsequently, the syndrome has been quoted as Váradi-Papp syndrome. AIM:To present the 25-year ...

journal_title：Orvosi hetilap

authors： Váradi V,Papp Z

更新日期：2005-09-25 00:00:00

abstract：:Improvement of muscle mass and force which got depleted by inactivity or pathological processes is one of the aims and also a prerequisite of a rehabilitative intervention. Metabolically active larger and stronger muscles diminish the cardiovascular risk, permit the aerobic preventive and rehabilitative activities and...

journal_title：Orvosi hetilap

authors： Apor P,Tihanyi J,Borka P

更新日期：2005-09-18 00:00:00

abstract：UNLABELLED:The effect of supplementary Vitamin E on the vitamin content of lipoproteins in young men and women. Inappropriate vitamin and trace element supplementation may facilitate the development of atherosclerosis. It is known that Vitamin E protects lipids from oxidative stress, while clinical signs of atheroscler...

journal_title：Orvosi hetilap

authors： Somogyi A,Herold M,Kocsis I,Nagy G,Somfai G,Studinger P

更新日期：2005-08-28 00:00:00

abstract：:The third Hungarian national dietary survey was conducted in 2003-2004. This publication describes the first part of the energy and nutrient intake findings in a sample consisting of a population of 1179 persons over 19 years of age (energy and macro nutrients). Energy and nutrient intake values were calculated based ...

journal_title：Orvosi hetilap

authors： Rodler I,Bíró L,Greiner E,Zajkás G,Szórád I,Varga A,Domonkos A,Agoston H,Balázs A,Mozsáry E,Vitrai J,Hermann D,Boros J,Németh R,Kéki Z

更新日期：2005-08-21 00:00:00

abstract：:Lycopene is a carotenoid found predominantly in tomatoes and tomato products. In contrast to beta-carotene it is not a precursor of vitamin A in humans. Lycopene is not destroyed during food processing, moreover its bioavailability improves. Lycopene is the most powerful antioxidant amongst carotenoids. Beside the ant...

journal_title：Orvosi hetilap

authors： Bánhegyi G

更新日期：2005-07-31 00:00:00

abstract：INTRODUCTION:The congenital or acquired anomalies of uterus could be the causes of complications in obstetrics. PATIENTS AND METHODS:157 patients were diagnosed by hysterosalpingography and/or ultrasound as having subseptate uterus which were assumed to be responsible for their recurrent abortions (124 cases) or infer...

journal_title：Orvosi hetilap

authors： Papp Z

更新日期：2005-07-10 00:00:00